abstract：:We report on a 10-year-old girl who was presented to the Emergency Department with a 3-day history of "vaginal bleeding", the cause of which was determined to be urethral prolapse. Urethral prolapse occurs when the urethra mucosa evaginates beyond the urethral meatus. This uncommon condition in prepubescent girls shou...

journal_title：European journal of pediatrics

authors： Shavit I,Solt I

更新日期：2008-05-01 00:00:00

abstract：:We describe an outbreak of echovirus type 18 infection involving 20 neonatal intensive care unit (NICU) patients and the results of virological investigations are presented. RT-PCR demonstrated a widespread transmission of the virus in NICU patients during the outbreak. Separation care and additional infection control...

journal_title：European journal of pediatrics

authors： Kusuhara K,Saito M,Sasaki Y,Hikino S,Taguchi T,Suita S,Hayashi J,Wakatsuki K,Hara T

更新日期：2008-05-01 00:00:00

abstract：UNLABELLED:The aim of this study was to obtain comprehensive data on clinical presentation, microbiology, computed tomography, surgical findings and histology in acute, sub-acute and chronic mastoiditis. We performed a prospective, observational study in children under 16 years of age presenting to our institution duri...

journal_title：European journal of pediatrics

authors： Stähelin-Massik J,Podvinec M,Jakscha J,Rüst ON,Greisser J,Moschopulos M,Gnehm HE

更新日期：2008-05-01 00:00:00

abstract：:Hypoparathyroidism is one of the recognized causes of late-onset neonatal hypocalcemia. Maternal hypercalcemic hyperparathyroidism has been shown to suppress fetal parathyroid glands, causing transient neonatal hypoparathyroidism. We report two siblings (6 years apart) with transient hypoparathyroidism presented with ...

journal_title：European journal of pediatrics

authors： Poomthavorn P,Ongphiphadhanakul B,Mahachoklertwattana P

更新日期：2008-04-01 00:00:00

abstract：:This study is a retrospective analysis of seven patients with hypoechogenic lesions in the liver and/or spleen due to Bartonella henselae, who were followed from 1998 through to 2005 by the Department of Pediatrics, Turin University. In addition to showing constitutional symptoms, four children had skin lesions sugges...

journal_title：European journal of pediatrics

authors： Scolfaro C,Leunga GG,Bezzio S,Chiapello N,Riva C,Balbo L,Bertaina C,Tovo PA

更新日期：2008-04-01 00:00:00

abstract：:Hypoglycaemia in children can be a life-threatening situation that needs to be assessed rigorously in order to treat efficiently and avoid relapse that can be responsible for cerebral damage. The diagnosis of impairment in glucose homeostasis requires the knowledge of the mechanisms regulating blood glucose concentrat...

journal_title：European journal of pediatrics

authors： Valayannopoulos V,Romano S,Mention K,Vassault A,Rabier D,Polak M,Robert JJ,de Keyzer Y,de Lonlay P

更新日期：2008-03-01 00:00:00

abstract：:The effects of perinatal problems on red cell phosphate metabolism were studied in two groups of infants (preterms B and fullterms D) during the first month of life. All infants started milk feeding from day three after birth. The results were compared to those of healthy preterms (A) and fullterms (C), respectively. ...

journal_title：European journal of pediatrics

authors： Cholevas V,Challa A,Lapatsanis PD,Andronikou S

更新日期：2008-02-01 00:00:00

abstract：:Spontaneous pneumomediastinum is uncommon in paediatric practice. We describe two cases of spontaneous pneumomediastinum in a child and an adolescent with anorexia nervosa. Thorough investigation failed to reveal any underlying cause for secondary pneumomediastinum. Pneumomediastinum in anorexia nervosa can be caused ...

journal_title：European journal of pediatrics

authors： van Veelen I,Hogeman PH,van Elburg A,Nielsen-Abbring FW,Heggelman BG,Mahieu HF

更新日期：2008-02-01 00:00:00

abstract：:We describe the natural history of the RTSII phenotype in a 7-year-old boy who developed intrauterine and postnatal growth retardation, failure to thrive and persisting diarrhoea. The growth hormone stimulation test identified an isolated growth hormone deficiency. Since infancy, the patient manifested skin lesions ch...

journal_title：European journal of pediatrics

authors： Sznajer Y,Siitonen HA,Roversi G,Dangoisse C,Scaillon M,Ziereisen F,Tenoutasse S,Kestilä M,Larizza L

更新日期：2008-02-01 00:00:00

abstract：:Cardiac imaging has had significant influence on the science and practice of pediatric cardiology. Especially the development and improvements made in non-invasive imaging techniques, like echocardiography and cardiac magnetic resonance imaging (MRI), have been extremely important. Technical advancements in the field ...

journal_title：European journal of pediatrics

authors： Mertens L,Ganame J,Eyskens B

更新日期：2008-01-01 00:00:00

abstract：:Primary hyperparathyroidism is a rare endocrine disease in children and young adults. The early detection and treatment of primary hyperparathyroidism led to a marked decrease in classical bone and renal manifestations of the disease. Osteitis fibrosa cystica and brown tumors have become extremely rare clinical entiti...

journal_title：European journal of pediatrics

authors： Atabek ME,Pirgon O,Sert A,Esen HH

更新日期：2008-01-01 00:00:00

abstract：:Cardiac function is impaired in adults or children with hypothyroidism and it can be reversed by levothyroxine (L-T(4)) substitution therapy. However, only a few studies are available on left and right ventricular function in neonates with congenital hypothyroidism (CH), most of which were performed with standard echo...

journal_title：European journal of pediatrics

authors： Mao S,Wang Y,Jiang G,Zhao Z

更新日期：2007-12-01 00:00:00

abstract：UNLABELLED:Successful therapy of vasodilatory shock in adults and children with arginine-vasopressin (AVP) has been reported previously. Data on the use of vasopressin in neonates is limited. This retrospective study reports the effects of AVP-treatment in neonates with catecholamine-resistant systemic vasodilatation a...

journal_title：European journal of pediatrics

authors： Lechner E,Hofer A,Mair R,Moosbauer W,Sames-Dolzer E,Tulzer G

更新日期：2007-12-01 00:00:00

abstract：:Newborns are exposed to mechanical and oxidative stress during labor and to relative hyperoxia thereafter during the course of adaptation to the extrauterine conditions. Part of the adaptation mechanism is the rapid degradation of fetal hemoglobin and the oxidation of its heme moiety by heme oxygenases (HOs). Heme oxy...

journal_title：European journal of pediatrics

authors： Maróti Z,Katona M,Orvos H,Németh I,Farkas I,Túri S

更新日期：2007-10-01 00:00:00

abstract：:A large number of ventilation strategies are now available for the neonate. This review has focused on new information, that is, studies published since 2000 and the implication of their results for current clinical practice. Meta-analysis of randomised trials has demonstrated that assist control and synchronous inter...

journal_title：European journal of pediatrics

authors： Greenough A,Sharma A

更新日期：2007-10-01 00:00:00

abstract：INTRODUCTION:Newborns with intrauterine growth retardation (IUGR) have multiple risk factors for developing hypoglycaemia. Hyperinsulinism, both transient and prolonged, is one of the major risk factors responsible for the hypoglycaemia observed in some newborns with IUGR. Once the child has progressed beyond the infan...

journal_title：European journal of pediatrics

authors： Kochar IS,Hussain K

更新日期：2007-10-01 00:00:00

abstract：:We present a case of Pott's disease, where the patient presented with neurological impairment due to vertebral granulomatous necrosis, needing immediate decompression and later stabilizing and reconstructive orthopaedic surgery, in order to create awareness for TB in general, especially this forgotten form of spinal t...

journal_title：European journal of pediatrics

authors： van Well GT,van der Mark LB,Vermeulen RJ,van Royen BJ,Wuisman PI,van Furth AM

更新日期：2007-10-01 00:00:00

abstract：:Tinea of the nails is not an exclusively adult pathology. The pediatrician should include this entity in the differential diagnosis. ...

journal_title：European journal of pediatrics

authors： Martinez Roig A,Torres Rodriguez JM

更新日期：2007-09-01 00:00:00

abstract：:Most drugs that are currently prescribed in pediatrics have not been tested in children. Pediatric drug studies are stimulated in the USA by the pediatric exclusivity provision under the Food and Drug Administration Modernization Act (FDAMA) that grants patent extensions when pediatric labeling is provided. We investi...

journal_title：European journal of pediatrics

authors： Boots I,Sukhai RN,Klein RH,Holl RA,Wit JM,Cohen AF,Burggraaf J

更新日期：2007-08-01 00:00:00

abstract：:The role of the type-2 T helper (Th2) cell-mediated immune response in the immunopathogenesis of atopic dermatitis (AD) is well documented. Whether polarized immunoresponse is confined to antigen-specific T cells or is distributed among all T cell subsets is still controversial. We investigated frequencies of interleu...

journal_title：European journal of pediatrics

authors： Machura E,Mazur B,Kwiecień J,Karczewska K

更新日期：2007-08-01 00:00:00

abstract：:Despite being one of the most common congenital defects in boys, the etiology of hypospadias remains largely unknown. In this case-referent study, we evaluated a wide spectrum of potential risk factors for hypospadias. Cases were identified from the hospital information system, and referents were recruited through the...

journal_title：European journal of pediatrics

authors： Brouwers MM,Feitz WF,Roelofs LA,Kiemeney LA,de Gier RP,Roeleveld N

更新日期：2007-07-01 00:00:00

abstract：:We report on a newborn infant with complex congenital heart disease (CHD) featuring double outlet right ventricle and hypoplastic left ventricle who had postductal oxygen saturation well above 95% and thus eluded pulse oximetry screening for CHD. ...

journal_title：European journal of pediatrics

authors： Hetzel PG,Glanzmann R,Günthard J,Bruder E,Godi E,Bührer C

更新日期：2007-06-01 00:00:00

abstract：INTRODUCTION:This randomised, observer-blind clinical trial conducted in Turkey evaluated the immunogenicity, safety and interchangeability of three paediatric inactivated hepatitis A vaccines in 424 seronegative children between 1 and 15 years of age. METHODS:Potential subjects were screened for anti-hepatitis A viru...

journal_title：European journal of pediatrics

authors： Soysal A,Gokçe I,Pehlivan T,Bakir M

更新日期：2007-06-01 00:00:00

abstract：:Henoch-Schonlein purpura (HSP) is an inflammatory vasculitis involving the skin, joints, gastrointestinal (GI) tract, and kidneys. This is the first case report describing a 5-year-old girl with HSP presenting duodenal involvement which might be associated with superior mesenteric artery syndrome (SMAS). ...

journal_title：European journal of pediatrics

authors： Harada T,Machida H,Ito S,Aihara Y,Yokota S

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The severity of childhood gastroenteritis is generally believed to be age-related rather than aetiology-related. Rotavirus-induced gastroenteritis is more severe than gastroenteritis caused by other enteric pathogens and is also age-related. We thus addressed the question of whether the increased severity of...

journal_title：European journal of pediatrics

authors： Albano F,Bruzzese E,Bella A,Cascio A,Titone L,Arista S,Izzi G,Virdis R,Pecco P,Principi N,Fontana M,Guarino A

更新日期：2007-03-01 00:00:00

abstract：:Failure to thrive, feeding difficulties, variable forms of infantile epilepsy or psychomotor developmental delay and hypotonia were the most frequent clinical disease presentations in eight children with combined oxidative phosphorylation enzyme complex deficiencies carrying mutations in the polymerase gamma (POLG1) g...

journal_title：European journal of pediatrics

authors： de Vries MC,Rodenburg RJ,Morava E,van Kaauwen EP,ter Laak H,Mullaart RA,Snoeck IN,van Hasselt PM,Harding P,van den Heuvel LP,Smeitink JA

更新日期：2007-03-01 00:00:00

abstract：:Chronic hepatitis B virus infection is among the most common causes of chronic liver disease in children. The aim of this study was to document prospectively our experiences related to lamivudine and high-dose interferon-alpha2a combination in naïve, e antigen positive, chronic hepatitis B virus infection treatment in...

journal_title：European journal of pediatrics

authors： Yilmaz A,Akcam M,Gelen T,Artan R

更新日期：2007-03-01 00:00:00

abstract：:Chronic granulomatous disease (CGD) is a rare primary immunodeficiency caused by mutations of one of the subunits of phagocyte reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase leading to decreased or complete absence of neutrophil oxidative burst. We report the clinical and laboratory findings in tw...

journal_title：European journal of pediatrics

authors： Chollet-Martin S,Lopez A,Gaud C,Henry D,Stos B,El Benna J,Chedevile G,Gendrel D,Gougerot-Pocidalo MA,Grandchamp B,Gérard B

更新日期：2007-02-01 00:00:00

abstract：:This study aimed to estimate the number of infants who died of unrecognized congenital adrenal hyperplasia (CAH) in Austria and the Czech Republic within the past 13 years, before the introduction of adequate neonatal screening. The study was based on retrospective analysis of neonatal screening cards of 242 infants w...

journal_title：European journal of pediatrics

authors： Strnadová KA,Votava F,Lebl J,Mühl A,Item C,Bodamer OA,Torresani T,Bouska I,Waldhauser F,Sperl W

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Human immunodeficiency virus type 1 (HIV-1) infected children treated with highly active antiretroviral therapy (HAART) may develop a significant reduction of plasma viremia associated with an increase in CD4+ T-cell counts. Functional capacity of this reconstituted immune system in response to recall antige...

journal_title：European journal of pediatrics

authors： Ching N,Deville JG,Nielsen KA,Ank B,Wei LS,Sim MS,Wolinsky SM,Bryson YJ

更新日期：2007-01-01 00:00:00

abstract：:This study gives, for the first time, an estimate of the incidence and the cost of rotavirus infection in day care centers in Lyon, France. ...

journal_title：European journal of pediatrics

authors： Floret D,Lina B,Pinchinat S,Billaud G,Aït-Belghiti F,Largeron N,Bellemin B,Trang CN,Fau C,Gaspard C,Mamoux V,Marcelon L

更新日期：2006-12-01 00:00:00

abstract：INTRODUCTION:Population modelling using mixed-effects models provides a means to study variability in drug responses among individuals representative of those for whom the drug will be used clinically. DISCUSSION:The advantages of these models in paediatric studies are that they can be used to analyse sparse data, sam...

journal_title：European journal of pediatrics

authors： Anderson BJ,Allegaert K,Holford NH

更新日期：2006-11-01 00:00:00

abstract：PURPOSE:The study investigated the television watching habits of children in hospital compared with those at home and the factors which influence them. METHODS:A random sample of 546 school aged children hospitalized in paediatric hospitals (2) in Athens (Greece) was studied. RESULTS:Children's television watching ti...

journal_title：European journal of pediatrics

authors： Matziou V,Zachos I,Kletsiou H,Triantafyllidou A,Tsoumakas C

更新日期：2006-11-01 00:00:00

abstract：:Congenital high airway obstruction syndrome (CHAOS) is a rare prenatal diagnosis consisting of a typical fetal triad of large hyperechogenic lungs, flattened or inverted diaphragms and ascites. Most cases are sporadic with unknown incidence. Before attempts of fetoscopic fetal salvage or ex utero intrapartum treatment...

journal_title：European journal of pediatrics

authors： Vanhaesebrouck P,De Coen K,Defoort P,Vermeersch H,Mortier G,Goossens L,Smets K,Zecic A,Vandaele S,De Baets F

更新日期：2006-10-01 00:00:00

abstract：INTRODUCTION:Prevention of obesity and overweight is an important target for health promotion. Early prevention requires an intervention during childhood and adolescence. At these stages, the game could be an appropriate means to teach nutrition knowledge and to influence dietary behaviour. To this end, the authors dev...

journal_title：European journal of pediatrics

authors： Amaro S,Viggiano A,Di Costanzo A,Madeo I,Viggiano A,Baccari ME,Marchitelli E,Raia M,Viggiano E,Deepak S,Monda M,De Luca B

更新日期：2006-09-01 00:00:00

abstract：OVERVIEW:In newborns with symptomatic congenital cytomegalovirus (CMV) infection, neuroimaging is the best available predictor of neurodevelopmental outcome. Cerebrospinal fluid (CSF) findings in congenital CMV infection have seldom been described. Neonates with central nervous system infections present high CSF Beta(2...

journal_title：European journal of pediatrics

authors： Alarcon A,Garcia-Alix A,Cabañas F,Hernanz A,Pascual-Salcedo D,Martin-Ancel A,Cabrera M,Tagarro A,Quero J

更新日期：2006-09-01 00:00:00

abstract：:We report on a youngster followed by his paediatrician from birth until 14 years of age for premature beats, most likely of ventricular origin. The sudden death of his sister provoked a re-assessment of his electrocardiograms (ECG), resulting in the diagnosis of Brugada syndrome and the subsequent implantation of a ca...

journal_title：European journal of pediatrics

authors： Mivelaz Y,Di Bernardo S,Pruvot E,Meijboom EJ,Sekarski N

更新日期：2006-08-01 00:00:00

abstract：INTRODUCTION:Impaired vitamin K status in cystic fibrosis (CF) has been considered as a newly emerged pathogenetic factor for reduced bone mineral density (BMD). OBJECTIVES:Our aim was to evaluate the effectiveness of vitamin K supplementation in managing bone formation abnormalities in children and adolescents with C...

journal_title：European journal of pediatrics

authors： Nicolaidou P,Stavrinadis I,Loukou I,Papadopoulou A,Georgouli H,Douros K,Priftis KN,Gourgiotis D,Matsinos YG,Doudounakis S

更新日期：2006-08-01 00:00:00

abstract：UNLABELLED:The importance of ultrasonography after the first febrile urinary tract infection has been recently challenged. The aim of this study was to evaluate the role of ultrasonography in detection of significant non-reflux abnormalities in the kidneys and the urinary tract, and to determine whether these findings ...

journal_title：European journal of pediatrics

authors： Jahnukainen T,Honkinen O,Ruuskanen O,Mertsola J

更新日期：2006-08-01 00:00:00

abstract：INTRODUCTION:Randomly estimated fasting hyperglycaemia in an asymptomatic individual may represent the first sign of pancreatic beta-cell dysfunction. OBJECTIVE:We aimed at specifying the genetic aetiology of asymptomatic hyperglycaemia in a cohort of children and adolescents. SUBJECTS AND METHODS:We analysed the aet...

journal_title：European journal of pediatrics

authors： Feigerlová E,Pruhová S,Dittertová L,Lebl J,Pinterová D,Kolostová K,Cerná M,Pedersen O,Hansen T

更新日期：2006-07-01 00:00:00